2-(6-chloropyrimidin-4-yl)acetic acid

2-(6-chloropyrimidin-4-yl)acetic acid - Names and Identifiers

Name	Methyl 2- (6- chloropyrimidin- 4- yl) acetate
Synonyms	acetate 2-(6-chloropyrimidin-4-yl)acetic acid methyl 2-(6-chloropyrimidin-4-yl)acetate 2-(azepan-4-yl)-1,2,3,4-tetrahydroisoquinoline 4-Pyrimidineacetic acid, 6-chloro-, methyl ester 2-(6-chloro-4-pyrimidinyl)acetic acid methyl ester
CAS	1097779-00-4

2-(6-chloropyrimidin-4-yl)acetic acid - Physico-chemical Properties

Molecular Formula	C7H7ClN2O2
Molar Mass	186.6
Storage Condition	Room Temprature

2-(6-chloropyrimidin-4-yl)acetic acid - Introduction

Methyl 6-chloro-4-acetate Pyrimidine is an organic compound with the chemical formula C8H8ClNO2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
1. appearance: 6-chloro -4-acetic acid methyl pyrimidine is a colorless clear liquid.
2. Melting point: about -5°C.
3. Boiling point: about 95°C.
4. Density: about 1.30 g/mL.
5. Solubility: Soluble in ethanol, ether and organic solvents, insoluble in water.

Use:
6-Chloro-4-acetic acid methyl pyrimidine is commonly used as a pesticide intermediate and can be used to synthesize other organic compounds. The compound can be used as a building block of heterocyclic compounds, and has a wide range of applications, such as drug synthesis, pesticide research and development.

Preparation Method:
The preparation of 6-chloro-4-acetic acid methyl pyrimidine is usually carried out by the following steps:
1. The formate reacts with bromoacetic acid to generate methyl acetate.
2. Methyl acetate and pyrimidine are added to the reaction system and reacted under alkaline conditions.
3. Methyl 6-chloro-4-acetate pyrimidine was extracted and separated from the reaction mixture.
4. Refine and get the final product.

Safety Information:
1. 6-Chloro-4-acetic acid methyl pyrimidine should be kept away from open flames and high temperatures, and stored in a sealed container away from direct sunlight.
2. Wear suitable protective gloves, goggles and protective clothing when using or coming into contact with the compound, and ensure that the work area is well ventilated.
3. Avoid inhaling the vapor or dust of the compound, and avoid contact with skin, eyes and clothing.
4. Be careful when handling the compound to prevent accidental splashing or swallowing.
5. If contact or inhalation occurs, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 15:17:50